Lukyanenko, V., J. Muriel, D. Garman, L. Breydo and R.J. Bloch (2022). Elevated Ca2+ at the Triad Junction Underlies Dysregulation of Ca2+ Signaling in Dysferlin-null Skeletal Muscle. Front. Physiol. 103, 1032447 [PMID: 36406982]
Muriel, J., V. Lukyanenko, T. Kwiatkowski, S. Battacharya, D. Garman, N. Weisleder and R.J. Bloch (2022) The C2 Domains of Dysferlin: Roles in Membrane Localization, Stabilization of Ca2+ Signaling, and Membrane Repair. J. Physiol. 600, 1953-1968 [PMID: 35156706; PMC9285653]
Kinney, C.J., A. O’Neill, K. Noland, W. Huang, V. Lukyanenko, M.R. Kane, C.W. Ward, A. F. Collier, J.A. Roche, J.C. McLenithan, P.W. Reed, and R.J. Bloch (2021) μ-Crystallin in Mouse Skeletal Muscle Promotes a Shift from Glycolytic toward Oxidative Metabolism. Curr. Res. Physiol. 4, 47-29. [PMID:34746826; PMCID: PMC8562245]
Kinney, C.J., and R.J. Bloch (2021) µ-Crystallin: A Thyroid Hormone Binding Protein. Endocr. Regulations 55, 89-102 [PMID: 34020530; PMC9202446]
Garcia-Pelagio, K.P., and R.J. Bloch (2021) Biomechanical Properties of the Sarcolemma and Costameres of Skeletal Muscle Lacking Desmin. Front. Physiol. 12, 706806 [PMID:34489727; PMC8416993]
Zhang, H., V. Bryson, C. Wang, T. Yu, J. Kerr, R. Wilson, D. Muoio, R.J. Bloch, C. Ward and P. Rosenberg (2021) Desmin Interacts with STIM1 and Coordinates Ca2+ Signaling in Skeletal Muscle. JCI Insight 6, e143472 [PMID: 34494555; PMC8492340]
Muriel, J.M., A. O’Neill, J.P. Kerr, E. Kleinhans-Welte, R.M. Lovering and R.J. Bloch (2020) Keratin 18 is an Integral Part of the Intermediate Filament Network in Murine Skeletal Am. J. Physiol., Cell Physiol. 318, C215-C224 [PMID:31721615; PMC6985829]
Mueller, A.L., and R.J. Bloch (2019) Skeletal Muscle Cell Transplantation: Models and Methods. J. Muscle Res. Cell Motil. 41, 297-311 [PMID: 31392564]
Mueller, A.L., A. O’Neill, T.I. Jones, A. Llach-Martinez, L.A. Rojas, P. Sakellariou, G. Stadler, W.E. Wright, D. Eyerman, P.L. Jones, R.J. Bloch (2019) Muscle Xenografts Reproduce Key Molecular Features of Facioscapulohumeral Muscular Dystrophy. Exp. Neurol 320:113011. doi: 10.1016/ j.expneurol.2019.113011. [Epub ahead of print] [PMID:31306642]
García-Pelagio K.P., L. Chen, H.C. Joca, C. Ward, W.J. Lederer, and R.J. Bloch (2018) Absence of Synemin in Mice causes Structural and Functional Abnormalities in Heart. J. Mol. Cell. Cardiol. 114, 354-363. [PMID:29247678; PMC5850968].
Collier, A.F., J. Gumerson, KK. Lehtimäki, J. Puoliväli, J.W. Jones, M.A. Kane, S. Manne, A. O’Neill, W.P. Windish, T. Ahtoniemi, B.A. Williams, D.E. Albrecht and R.J. Bloch (2018) Effect of Ibuprofen on Skeletal Muscle of Dysferlin-null Mice. J. Pharmacol. Exp. Ther. 364, 409-419. [PMID:2928466; PMC5801553]
Lukyanenko, V., J. Muriel and R.J. Bloch (2017) Coupling of Excitation to Ca2+
Release is Modulated by Dysferlin. J. Physiol. 595, 5191-5207. [PMID:28568606; PMC5538227]
Desmond, P.F., A. Labuza, J. Muriel, M.L. Markwardt, A.E. Mancini, M.A. Rizzo and R.J. Bloch (2017) Interactions of Small Ankyrin 1 and Sarcolipin Coordinately Regulate Activity of the Sarco(endo)plasmic Reticulum Ca2+-ATPase 1 (SERCA1) J. Biol. Chem. 292, 10961-10972. [PMID:28487373; PMC5491780].
Moorer, M.C, A.M. Buo, K.P. Garcia-Pelagio, J.P. Stains and R.J. Bloch (2016) Deficiency of the Intermediate Filament Synemin Reduces Bone Mass in Vivo. Am. J. Physiol. Cell Physiol. 311, C839-C845. [PMID:27605453; PMC5206296
Sakellariou, P., A. O’Neill, A.L. Mueller, G. Stadler, W.E. Wright, J.A. Roche and R.J. Bloch (2015) Neuromuscular Electrical Stimulation Promotes Development in Mice of Mature Human Muscle from Immortalized Human Myoblasts. Skeletal Muscle 6: 4. [PMID: 26925213; PMC4769538]
Desmond, P.F., J. Muriel, M.L. Markwardt, M.A. Rizzo and R.J. Bloch (2015) Identification of Small Ankyrin 1 as a Novel Sarco(endo)plasmic Reticulum Ca2+-ATPase 1 (SERCA1) Regulatory Protein in Skeletal Muscle. J. Biol. Chem. 290: 27854-27867. [PMID: 26405035; PMC4646913]
Roche, J.A., M.E. Tulapurkar, A.L. Mueller, N. van Rooijen, J.D. Hasday, R.M. Lovering and R.J. Bloch (2015) Myofiber Damage Precedes Macrophage Infiltration after In Vivo Injury in Dysferlin-deficient A/J Mouse Skeletal Muscle. Am. J. Pathol. 185: 1686-1698. [PMID: 25920768; PMC4450316]
Banks, G.B., A.C. Combs, G.L. Odom, R.J. Bloch and J.S. Chamberlain (2014) Muscle Structure Influences Utrophin Expression in Mdx Mice. PLoS Genet.10:e1004431. [PMID: 24922526; PMC4055409].
Garcia-Pelagio, K., J. Muriel, A. O’Neill, P. Desmond, R. Lovering, L. Lund, M. Bond, and R.J. Bloch (2014) Myopathic Changes in Murine Skeletal Muscle Lacking Synemin. Am. J. Physiol. Cell Physiol. 308, C448-C462. [PMID: 25567810; PMC4360028].
Kerr, J.P., C.W. Ward and R.J. Bloch (2014) Dysferlin at Transverse Tubules Regulates Ca2+ Homeostasis in Skeletal Muscle. Frontiers Physiol 5, article 89. [PMID 24639655; PMC3944681].
Kerr, J.P., A.P. Ziman, A.L. Mueller, J.M. Muriel, E. Kleinhans-Welte, J.D. Gumerson, S.S. Vogel, C.W. Ward, J.A. Roche and R.J. Bloch (2013) Dysferlin Stabilizes Stress-induced Ca2+ Signaling in the Transverse Tubule Membrane. Proc. Natl. Acad. USA 110, 20831-20836. [PMID:24302765; PMC3870721].
Goodall, M.H., C.W. Ward, S.J. Pratt, R.J. Bloch and R.M. Lovering (2012) Structural and Functional Evaluation of Branched Myofibers Lacking Intermediate Filaments. Am. J. Physiol. Cell Physiol. 303, C224-C232. [PMID: 22592402; PMC3404518]
Lostal, W., M. Bartoli, C. Roudaut, N. Bourg, M. Krahn, M. Pryadkina, P. Borel, L. Suel, J.A. Roche, D. Stockholm, R.J. Bloch, N. Levy, R. Bashir, and I. Richard (2012) Lack of correlation between outcomes of membrane repair assay and correction of dystrophic changes in experimental therapeutic strategy in dysferlinopathy. PlOS One 2012, e38036. [PMID: 22666441; PMC3362551]
Reed, P., A. Densmore, and R.J. Bloch (2012) Optimization of Large Gel 2D Electrophoresis for Proteomic Studies of Skeletal Muscle. Electrophoresis 33, 1263-1270. [PMID:22589104; PMC3822429]
Willis, C.D., T. Oashi, B. Busby, A.D. MacKerell Jr., and R.J. Bloch (2012) Hydrophobic Contribution to Binding of Obscurin and Small Ankyrin 1. Mol. Memb. Biol. 29, 36-51. [PMID: 22416964; PMC3377380]
Roche, J.A., L.W. Ru, and R.J. Bloch (2012) Distinct Effects of Contraction-induced Injury In Vivo on Four Different Murine Models of Dysferlinopathy. J. Biotechnol. Biomed. 2012, 134031. [PMID:22431915; PMC3303924]
Shah, S.B., J.M. Love, A. O’Neill, R.M. Lovering and R.J. Bloch (2012) Influences of Desmin and Keratin 19 on Passive Biomechanical Properties of Mouse Skeletal Muscle. J. Biotechnol. Biomed. 2012, 704061. [PMID: 22287836; PMC3263816]
Lund, L.M., J.P. Kerr, J. Lupinetti, Y. Zhang, M.A. Russell, R.J. Bloch and M. Bond (2012). Synemin Isoforms Differentially Organize Cell Junctions and Desmin Filaments in Neonatal Cardiomyocytes. FASEB J. 26, 137-148. [PMID: 21982947; PMC3250239]
Roche, J.A., D.L. Ford-Speelman, L.W. Ru, A.L. Densmore, R. Roche, P.W. Reed and R.J. Bloch (2011) Physiological and Histological Changes in Skeletal Muscle Following in Vivo Gene Transfer by Electroporation. Am. J. Physiol. Cell Physiol. 301, C1239-C1250. [PMID: 21832248; PMC3213910].
Roche, J.A., L. Ru, A. O’Neill, R. Lovering and R.J. Bloch (2011) Unmasking Intracellular Dysferlin. J. Histochem. Cytochem. 59, 964-975. [PMID: 22043020; PMC3213910].
Ackermann, M.A., A.P. Ziman, J. Strong, C.W. Ward, W.R. Randall, A. Kontrogianni- Konstantopoulos, and R.J. Bloch (2011) Integrity of the Network Sarcoplasmic Reticulum in Skeletal Muscle Requires Small Ankyrin 1. J. Cell Sci. 124, 3619-3630. [PMID: 22045734; PMC3215573].
DiPasquale, D., R.J. Bloch and R.M. Lovering (2011) Determinants of the Repeated Bout Effect Following Lengthening Contractions. Am. J. Phys. Med. Rehab. 90, 816-824; Erratum 91, 308. [PMID: 21862912; PMC3169747].
Busby, B., T. Oashi, C.D. Willis, M.A Ackermann, A. Kontrogianni-Konstantopoulos, A.D. MacKerell Jr. and R.J. Bloch (2011) Electrostatic Interactions Mediate Binding of Obscurin to Small Ankyrin 1: Biochemical and Molecular Modeling Studies. J. Mol. Biol. 408, 321-334. [PMID: 21333652; PMC3367564].
Lovering, R.M., A. O’Neill, J.M. Muriel, B.L. Prosser, J. Strong and R.J. Bloch (2011) Physiology, Structure, and Susceptibility to Injury of Skeletal Muscle in Mice Lacking Keratin 19- Based and Desmin-Based Intermediate Filaments. Am. J. Physiol. Cell Physiol. 300, C803-C813. [PMID: 21209367; PMC3074621]
García-Pelagio, K., R.J. Bloch, A. Ortega and H. González-Serratos (2011) Biomechanics of the Sarcolemma and Costameres in Skeletal Myofibers from Normal and Dystrophic Mice. J. Musc. Res. Cell Motil. 31, 323–336. [PMID: 21312057; PMCID: PMC4326082]
Nestor, M.W., X. Cai, M.R. Stone, R.J. Bloch and S. Thompson (2011) The Actin Binding Domain of βI-Spectrin Regulates the Morphological and Functional Dynamics of Dendritic Spines. PLoS One 6, e16197. [PMID: 21297961; PMC3031527]
Cappello, R., G. Estrada-Gutierrez, C. Irles, S. Giono, R.J. Bloch and J. Nataro (2010) Fed. Europ. Microbiol. Soc. Immunol. Med. Microbiol. 61, 301-314. [PMID: 21205005; PMC3055947]
Busby, B., C.D. Willis, M.A. Ackermann, A. Kontrogianni-Konstantopoulos and R.J. Bloch (2010). Characterization and Comparison of Two Binding Sites on Obscurin for Small Ankyrin 1. Biochem. 49, 9948-9956. [PMID: 20949908; PMC3000613]
Ziman, A.P., C.W. Ward, G.G. Rodney, W.J. Lederer, and R.J. Bloch (2010) Quantitative Measurement of Ca2+ in the Sarcoplasmic Reticulum Lumen of Mammalian Skeletal Muscle. Biophys. J. 99, 2705-2714. [PMID: 20959112; PMC2955505]
Weinman, E.J., D. Steplock, Y. Zhang, R. Biswas, R.J. Bloch and S. Shenolikar (2010) Cooperativity between the Phosphorylation of Thr95 and Ser77 of NHERF-1 in the Hormonal Regulation of Renal Phosphate Transport. J. Biol. Chem. 285, 25134-25138. [PMID: 20571032; PMC2919075]
Zhang, Y., W.G. Resneck, P.C. Lee, D.H. Catino, D. Ford-Speelman, W.R. Randall, R.J. Bloch and J.A. Ursitti (2010) Characterization and Expression of a Heart-Specific, Alternatively Spliced Variant of αII-Spectrin, Cardi+, during Development in the Rat. J. Mol. Cell. Cardiol. 48, 1050-1059. Epub 2010 Jan 28. [Commentary: T.J Hund, P.J. Mohler, J. Mol. Cell. Cardiol. 48, 1031-1032. Epub 2010 Feb 6]. [PMID: 20114050; PMC3537504]
Roche, J.A., R.M. Lovering, R. Vanapalli, P.W. Reed and R.J. Bloch (2010) Extensive Mononuclear Infiltration and Myogenesis Characterize the Recovery of Dysferlin-Null Skeletal Muscle from Contraction-Induced Injuries. Am. J. Physiol. Cell Physiol. 298, C298-C312. [PMID: 19923419; PMC2822489]
Ziman A.P., N.L. GómZez-Viquez, R.J. Bloch and W.J. Lederer (2010) Excitation-Contraction Coupling Changes during Postnatal Cardiac Development. J. Mol. Cell. Cardiol. 48, 379-386. [PMID:19818794; PMC3097073]
Millay, D.P., M. Maillet, J.A. Roche, M.A. Sargent, E.M. McNally, R.J. Bloch, and J.D. Molkentin (2009) Genetic Manipulation of Dysferlin Expression in Skeletal Muscle: Novel Insights into Muscular Dystrophy. Am. J. Pathol. 175, 1817-1823. Epub 2009 Oct 15. [PMID:19834057; PMC2774048]
Ford-Speelman, D.L., A.L. Bowman, and R.J. Bloch (2009) The RhoGEF Domain of Obscurin Activates RhoA Signaling in Skeletal Muscle. Mol. Biol. Cell 20, 3905-3917. [PMID: 19605563; PMC2735489]
Kontrogianni-Konstantopoulos, A., M.A. Ackermann, A.L. Bowman, S.L. Yap and R.J. Bloch (2009) Muscle Giants: Molecular Scaffolds in Sarcomerogenesis. Physiol. Rev. 89, 1217-1267. [PMID: 19789381; PMC3076733]
Tang, W., R.M. Lovering, J.A. Roche, N.K. Neerchal, R.J. Bloch and U. Tasch. (2009) Gait Analysis of Locomotory Impairment in Rats Before and After Neuromuscular Injury. J. Neurosci. Meth. 181, 249-256. [PMID: 19433107; PMC3526839]
Ackermann, M.A., L-Y.R. Hu, A.L. Bowman, R.J. Bloch and A. Kontrogianni-Konstantopoulos (2009) Obscurin Interacts with a Novel Isoform of MyBP-C at the Periphery of the Sarcomeric M-Band and Regulates Thick Filament Assembly. Mol. Biol. Cell 20, 2963-2978. [PMID: 19403693; PMC2695803]
Roche, J.A., R.M. Lovering and R.J. Bloch (2008) Impaired Recovery of Dysferlin-null Skeletal Muscle after Contraction-Induced Injury In Vivo. NeuroReport 19, 1579-1584. [PMID: 19433107; PMC2662728]
Bowman, A.L., D. Catino, W.R. Randall, A. Kontrogianni-Konstantopoulos and R.J. Bloch (2008) The Rho-GEF Domain of Obscurin Binds to RanBP9 and Regulates Assembly of Titin at the Z-line. Mol. Biol. Cell 19, 3782-3792. [PMID: 18579686; PMC2526693]
Stone, M.R., A. O’Neill, R.M. Lovering, P.W. Reed, J. Strong, W.G. Resneck, P.C. Lee, D.M. Toivola, J.A. Ursitti, M.B. Omary and R. J. Bloch (2007) Absence of Keratin 19 in Mice Causes Skeletal Myopathy with Mitochondrial and Sarcolemmal Reorganization. J. Cell Sci. 120, 3999-4008. [PMID: 17971417]
Borzok, M.A., D.H. Catino, J.D. Nicholson, A. Kontrogianni-Konstantopoulos and R.J. Bloch (2007) Mapping the Binding Site on Small Ankyrin 1 for Obscurin. J. Biol. Chem. 282, 32384- 32396. [PMID:17720975]
Lovering, R.M., A. O’Neill, J. Roche and R.J. Bloch (2007) Identification of Mutants of Skeletal Muscle in Neonatal Mice by Immunofluorescence Studies of Tail Snips. Biotechniques 42, 702-704. [PMID: 17612291]
Reed, P.W., A.M. Corse, N.C. Porter, K.M. Flanigan and R.J. Bloch (2007) Abnormal Expression of mu-Crystallin in Facioscapulohumeral Muscular Dystrophy. Exp. Neurol. 205, 583-586. [PMID: 17451686]
Capetanaki, Y., R.J. Bloch, A. Kouloumenta, M. Mavroidis and S. Psarras (2007) Muscle Intermediate Filaments and their Links to Membranes and Membranous Organelles. Exp. Cell Res. 313, 2063-2076. [PMID: 17509566]
Bowman, A.L., A. Kontrogianni-Konstantopoulos, S.B. Geisler, H. Gonzalez-Serratos, M.W. Russell and R.J. Bloch (2007) Different Obscurin Isoforms Localize to Distinct Sites at Sarcomeres. FEBS Lett. 581, 1549-1554. [PMID: 17382936; PMC1899168]
Lovering, R.M., J.A. Roche, R.J. Bloch, and P.G. De Deyne (2007) Recovery of Function In Skeletal Muscle Following 2 Different Contraction-induced Injuries. Arch. Phys. Med. Rehab. 88, 617-625. [PMID: 17466731]
Ursitti, J.A., B.G. Petrich, P.C. Lee, X. Ye, J. Yang, W.R. Randall, R.J. Bloch, and Y. Wang (2007) Role of an Alternatively Spliced Form of AlphaII-Spectrin in Localization of Connexin 43 in Cardiomyocytes and Regulation by Strain-Activated Protein Kinase. J. Mol. Cell. Cardiol. 42, 572-581. [PMID: 17276456; PMC1983066]
Antolik, C., D.H. Catino, A. O’Neill, W.G. Resneck, J.A. Ursitti and R.J. Bloch (2007) The Actin-Binding Domain of ACF7 Binds Directly to the Tetratricopeptide Repeats of Rapsyn. Neurosci. 145, 56-65. [PMID: 17222516; PMC1868462]
Antolik, C., D.H. Catino, W.G. Resneck and R.J. Bloch (2006) The Tetratricopeptide Repeat Domains of Rapsyn Bind Directly to Cytoplasmic Sequences of the Muscle-Specific Kinase. Neurosci. 141, 87-100. [PMID: 16675143]
Kontrogianni-Konstantopoulos, A., D.H. Catino, J.C. Strong, S. Sutter, D.W. Pumplin, M.W. Russell and R.J. Bloch (2006) Obscurin Modulates the Assembly and Organization of Sarcomeres and the Sarcoplasmic Reticulum. FASEB J. 20, 2102-2111. [PMID: 17012262]
Reed, P., N.C. Porter, J. Strong, D.W. Pumplin, A.M. Corse, P.W. Luther, K.M. Flanigan, and R.J. Bloch (2006). Sarcolemmal Reorganization in Facioscapulohumeral Muscular Dystrophy. Ann. Neurol. 59, 289-297. [PMID: 16437580]
Kontrogianni-Konstantopoulos, A., D. Catino, J. Strong, and R.J. Bloch (2006) De novo Myofibrillogenesis in C2C12 Cells: Evidence for the Independent Assembly of M-lines and Z- disks. Am. J. Physiol. Cell Physiol. 290, C626-637. [PMID:16207790]
For a full bibliography, please see here.